Do the blood vessels in our brain "spit out" clots?

ClotCare: Blood Clots, Stroke, Heart Attack

Thursday, November 21, 2024

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Pick a Topic: Home New Postings Patient Postings Clinician Postings Join Our Email List Useful Web Links CE Opportunities Training Programs Guidelines DVT & PE Stories Editorial Board Financial Support About ClotCare DVT Coalition Contact Us Find info on a: Specific Medicine or Treatment Type of Medicine or Treatment Condition or Medical Procedure Lab Test Procedure Management Issue ClotCare complies with the HONcode standard for trustworthy health information: verify here. ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March.	Do the blood vessels in our brain "spit out" clots? Henry I. Bussey, Pharm.D. September, 2010 Even though the study was performed in animals, Lam and colleagues¹ reported in Nature a very interesting finding that there is a process by which some blood vessels in the brain can "absorb" blood clots into the wall of the blood vessel and then pass the clot on through the blood vessel wall and eject it into the perivascular space. In an editorial in the New England Journal of Medicine² discussing this study, the authors of the editorial point out that this process apparently takes days, rather than hours, and that the ability of the blood vessels to process clots in this fashion tends to decline with age. Obviously, numerous questions remain such as what triggers this process? What is the impact of the clot once it exits the blood vessel? How are such extravascular clots cleared or eliminated? Can measure be implemented to help blood vessels retain this ability? Does the same process occur in the human brain and, if so, does it occur in all regions of the brain? Perhaps further research in this area will provide new ways of treating and/or preventing or minimizing the impact of some strokes. References Lam CK Yoo T, Hiner B, Liu Z, Gritzendler J. Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization. Nature 2010; 465:478-82. del Zoppo GJ, Hawkins BT. Throwing out the thromboemboli. The New England Journal of Medicine 2010; 363:1282-1284.	Have questions? Ask ClotCare. Send questions by email to webmaster@clotcare.org. ClotCare is a 501(c)(3) non-profit organization generously supported by your tax-deductible donations and grants from our industry supporters. New Postings: Click here to view full list of new postings
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Key topics discussed on ClotCare include: Blood Clots \| Deep Vein Thrombosis (DVT) \| Pulmonary Embolism (PE) \| Atrial Fibrillation (A. Fib or AF) \| Heart Attack \| Stroke \| Transient Ischemic Attack (TIA) \| Mini Stroke \| Bleeding Complications \| Vascular Surgery \| Surgical Blood Clot Removal \| Warfarin \| Coumadin \| Lovenox \| Low Molecular Weight Heparin (LMWH) \| Heparin \| Anticoagulants \| Plavix \| Aspirin \| Antiplatelets \| Blood Thinners
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