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New Supplement Devoted to Factor Xa Inhibitors (fondaparinux)

Henry I. Bussey, Pharm.D.
August 2004

This supplement to the journal, Pharmacotherapy (Vol 24, Issue 7, Part 2, July, 2004), addresses current issues regarding the limitations of traditional anticoagulants and the evolving role of factor Xa inhibitors for short-term and long-term prophylaxis in orthopedic surgery, for treatment of venous thromboembolism, and for management of heparin-induced thrombocytopenia. The differential effects of anticoagulants on wound healing, and the pharmacoeconomics of thrombosis management also are discussed.

With the permission of Pharmacotherapy, we have made each article from the supplement available in pdf format. Click on an article's title to view the pdf.

Introduction-Current Concepts in Thrombosis Management: Focus on Factor Xa Inhibition
Authors: Edith A. Nutescu, Pharm.D.

Limitations of Traditional Anticoagulants
Authors: David Hawkins, Pharm.D.

Emerging Options for Thromboprophylaxis After Orthopedic Surgery: A Review of Clinical Data
Authors: Bob L. Lobo, Pharm.D.

Evidence for Extended Prophylaxis in the Setting of Orthopedic Surgery
Authors: Paul P. Dobesh, Pharm.D.

Evolving Concepts in the Treatment of Venous Thromboembolism: The Role of Factor Xa Inhibitors
Authors: Edith A. Nutescu, Pharm.D. and Cathy M. Helgason, M.D.

Special Considerations with Fondaparinux Therapy: Heparin-Induced Thrombocytopenia and Wound Healing
Authors: William E. Dager, Pharm.D., FCSHP, Judith Andersen, M.D. and Edith Nutescu, Pharm.D.

Pharmacoeconomics of Thrombosis Management
Authors: David Hawkins, Pharm.D.

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Blood Clot Activities Calendar

New Postings:

How Should We Prevent Blood Clots Following Arthroscopic Knee Surgery? Cynthia’s Story and a Limited Discussion of the Literature

Stroke, A Caregiver's Story

World Thrombosis Day - Oct. 13, 2017

Click here to view full list of new postings
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Tuesday, November 21, 2017