ClotCare: Blood Clots, Stroke, Heart Attack
Monday, June 26, 2017
Home   |   DVT/PE   |   Blood Clots   |   Coumadin/Warfarin   |   New Patients   |   Self Testing   |   Email List   |   Donate

Pick a Topic:

Find info on a:

We subscribe to the HONcode principles of the HON Foundation. Click to verify.
ClotCare complies with the HONcode standard for trustworthy health
information:
verify here.

ClotCare is a member of the Coalition to Prevent Deep Vein Thrombosis (DVT Coalition)  ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March.

"Mini Strokes" with Maximum Impact

Susan C. Fagan, Pharm.D., BCPS, FCCP
August, 2005

Review: Rothwell PM, Giles MF, Flossman E, Lovelock CE, Redgrave JNE, Warlow CP, Mehta Z. A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischemic attack. Lancet 2005;366:29-36.

If we needed any more convincing that patients who experience a transient ischemic attack (TIA) need prompt medical attention for the institution of appropriate secondary prevention therapies, here it is. In this report from a group of well-known stroke investigators from the UK, a simple method has been developed to predict which patients with a probable or definite TIA are at the highest risk for stroke in 7 days. The ABCD score, standing for, A=age 60 years or greater (1 point); B=blood pressure 140/90 or greater (1 point); C=clinical features of unilateral weakness (2 points) or speech disturbance without weakness (1 point); and D=duration of symptoms either 60 minutes or greater (2 points); 10-59 minutes (1 point), is easy to remember and correctly predicted those at the highest 7-day risk of stroke in two separate cohorts. The first cohort was used to derive the score, based on known predictors of recurrence, and the second, to validate it. The scoring system was very accurate with only 0.4% of patients with scores < 5 experiencing a stroke in 7 days, compared to 12.1% of patients with a score of 5 and 31.4% of patients getting the maximal 6 points.

The retrospective nature of the data used does not allow comment or comparisons between patients on different preventive therapies but it is likely that reductions in recurrence rates would be seen with optimal pharmacotherapeutic interventions started quickly after a TIA. In the UK, where TIA patients are often seen in busy outpatient clinics after delays of 2 weeks or more, the authors plead for sweeping changes in policy to make sure that the most "high-risk" TIA patients are seen urgently. This can be applied to other health care systems where decisions regarding prioritization of care must be made to ensure the patients at greatest need are seen first.

Ask a question about blood clots or anticoagulant medications Have questions? Ask ClotCare. Send questions by email to webmaster@clotcare.org.

ClotCare is a 501(c)(3) non-profit organization generously supported by your tax-deductible donations and grants from our industry supporters.

Blood Clot Activities Calendar

New Postings:

Research Company Seeks Patients who Have Had a Leg Blood Clot (deep vein thrombosis or DVT)

Click here to view full list of new postings
ClotCare Home | New Postings | Patient Postings | Clinician Postings | Join Our Email List | Useful Web Links
CE Opportunities | Training Programs | DVT & PE Stories | Editorial Board | Financial Support
About ClotCare | DVT Coalition | Donate to ClotCare | Contact Us
Key topics discussed on ClotCare include: Blood Clots | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Atrial Fibrillation (A. Fib or AF) | Heart Attack | Stroke | Transient Ischemic Attack (TIA) | Mini Stroke | Bleeding Complications | Vascular Surgery | Surgical Blood Clot Removal | Warfarin | Coumadin | Lovenox | Low Molecular Weight Heparin (LMWH) | Heparin | Anticoagulants | Plavix | Aspirin | Antiplatelets | Blood Thinners
Copyright 2000-2014 by ClotCare. All rights reserved.
Terms, Conditions, & Privacy | Image Copyright Information
19260 Stone Oak Parkway, Suite 101 | San Antonio, TX 78258 | 210-495-4335
Send comments to webmaster@clotcare.org.
Monday, June 26, 2017