ClotCare: Should Rofecoxib (Vioxx) Have Been Withdrawn Years Ago?

ClotCare: Blood Clots, Stroke, Heart Attack

Thursday, November 21, 2024

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Pick a Topic: Home New Postings Patient Postings Clinician Postings Join Our Email List Useful Web Links CE Opportunities Training Programs Guidelines DVT & PE Stories Editorial Board Financial Support About ClotCare DVT Coalition Contact Us Find info on a: Specific Medicine or Treatment Type of Medicine or Treatment Condition or Medical Procedure Lab Test Procedure Management Issue ClotCare complies with the HONcode standard for trustworthy health information: verify here. ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March.	Should Rofecoxib (Vioxx) Have Been Withdrawn Years Ago? Henry I. Bussey, Pharm.D., FCCP, FAHA November 2004 Review: Peter Jüni, Linda Nartey, Stephan Reichenbach, Rebekka Sterchi, Paul A Dieppe, Matthias Egger. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. Lancet 2004; 364, 9447.^* Swedish investigators conducted a meta analysis of 18 randomized controlled trials and 11 observational reports to conclude that data were adequate to warrant withdrawal of rofecoxib as early as 2000. Further, these investigators point out that FDA data often provide more thorough information than published studies, and they suggest that companies should perform continuous monitoring and evaluations of their products. ^*The full text of this article is available for free on The Lancet's website, but you may have to register to view it. Registration is free.	Have questions? Ask ClotCare. Send questions by email to webmaster@clotcare.org. ClotCare is a 501(c)(3) non-profit organization generously supported by your tax-deductible donations and grants from our industry supporters. New Postings: Click here to view full list of new postings
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Key topics discussed on ClotCare include: Blood Clots \| Deep Vein Thrombosis (DVT) \| Pulmonary Embolism (PE) \| Atrial Fibrillation (A. Fib or AF) \| Heart Attack \| Stroke \| Transient Ischemic Attack (TIA) \| Mini Stroke \| Bleeding Complications \| Vascular Surgery \| Surgical Blood Clot Removal \| Warfarin \| Coumadin \| Lovenox \| Low Molecular Weight Heparin (LMWH) \| Heparin \| Anticoagulants \| Plavix \| Aspirin \| Antiplatelets \| Blood Thinners
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